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Image Search Results
Journal: AAPS PharmSciTech
Article Title: PEGylated Lipid Polymeric Nanoparticle–Encapsulated Acyclovir for In Vitro Controlled Release and Ex Vivo Gut Sac Permeation
doi: 10.1208/s12249-020-01810-0
Figure Lengend Snippet: DSC Setting for Thermal Analysis of Each Sample
Article Snippet:
Techniques: Formulation
Journal: AAPS PharmSciTech
Article Title: PEGylated Lipid Polymeric Nanoparticle–Encapsulated Acyclovir for In Vitro Controlled Release and Ex Vivo Gut Sac Permeation
doi: 10.1208/s12249-020-01810-0
Figure Lengend Snippet: Stacked spectra of ATR-FTIR from 4000 to 600 cm −1 for PALNs, physical mixture, acyclovir, lecithin, chitosan, and PEG 2000
Article Snippet:
Techniques:
Journal: AAPS PharmSciTech
Article Title: PEGylated Lipid Polymeric Nanoparticle–Encapsulated Acyclovir for In Vitro Controlled Release and Ex Vivo Gut Sac Permeation
doi: 10.1208/s12249-020-01810-0
Figure Lengend Snippet: Amount, Percentage of Acyclovir Permeated, and Apparent Permeability at Each Time Point
Article Snippet:
Techniques: Permeability
Journal: Viruses
Article Title: Ginkgolic Acid Inhibits Herpes Simplex Virus Type 1 Skin Infection and Prevents Zosteriform Spread in Mice
doi: 10.3390/v13010086
Figure Lengend Snippet: GFP-HSV-1 average zosteriform infection scores of BALB/cJ mice (N = 10/treatment), following the application of DMSO in 2.5% HydroxyEthyl Cellulose (HEC) gel, 10 mM GA in HEC gel, and ACV USP 5%. ( A ) Age-matched BALB/cJ mice were inoculated with 6 × 10 4 PFU of GFP-HSV-1, given respective treatments, and monitored for survival for 14 days. ( B ) Averaged infection scores of surviving animals in each treatment group across 14 days. ( C ) Combined and averaged infection score of all animals per day for 14 days. GA-treated animals demonstrated a significant reduction in the appearance of vesicles and erosions compared to vehicle-treated control animals. ( B ) Student independent t -tests (2-tailed) and ( C ) One-way ANOVA [F(2, 39) = 12.31]; * p < 0.05, ** p < 0.001. Δ indicates that 8 out of 10 animals in the DMSO-treated group died by day 12 p.i. All error bars represent SEM.
Article Snippet: The inoculation sites on the mice (N = 10/treatment group) were treated with 10% DMSO (vehicle-control) formulated in 2.5% HEC gel, 10 mM GA in 2.5% HEC gel, or acyclovir (ACV) ointment,
Techniques: Infection, Control